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New sensing tool could aid in early detection of Dengue virus

first_img Source:https://www.bath.ac.uk/announcements/new-technology-could-detect-dengue-fever-earlier/ Reviewed by Kate Anderton, B.Sc. (Editor)Mar 12 2019Dr Paulo Rocha from the University of Bath’s Department of Electronic & Electrical Engineering is developing a low-cost integrative sensing tool for early detection of Dengue virus, using a novel platform containing electrical sensors to investigate the behavior of human cells infected with Dengue virus.When someone is infected by the Dengue virus it produces proteins, particularly ‘non-structural protein 1’ (NS1) which is secreted from infected cells. Using a three centimeter squared platform, the Bath-based research team will observe the electrical behavior of human cells in vitro infected by different concentrations of NS1.A better understanding of the electrical behavior of these cells, the researchers believe, will help create a more accurate and sensitive way of detecting the presence of Dengue virus.Related StoriesThe return of the measles: are we going backward?Puzzling paralysis affecting healthy children warns CDCExperts find previously unknown bacterial strain of the genus LeptospiraIn the future, it is hoped this research will lead to the development of a low cost, disposable, real-time wearable system for detecting Dengue fever as well as Zika virus and Yellow Fever virus, both of which belong to the same Flaviviridae family. This will be of particular benefit to communities in developing countries where access to healthcare may be limited and Dengue fever is particularly prevalent.Dengue fever is an incurable mosquito-borne tropical disease initiated by the Dengue virus. It is spread by mosquitos mostly in tropical and subtropical areas of the world with symptoms ranging from fever and muscle/joint pains to life-threatening Dengue hemorrhagic fever. Each year it is estimated 390 million dengue infections occur around the world. Of these, 500,000 cases develop into dengue hemorrhagic fever which results in up to 25,000 deaths annually worldwide.A method that doctors currently adopt to test for Dengue fever is by examining the presence of NS1 in a patient’s bloodstream through a simple blood test. However, many people who are infected by Dengue virus may not be diagnosed due to the concentration of NS1 being so low and therefore not detected. This prevents correct diagnosis and the early intervention of drugs to counteract and reduce the effects of the virus.Lead researcher and Assistant Professor in the University of Bath’s Department of Electronic & Electrical Engineering, Dr Paulo Rocha, said: “If we can detect Dengue fever earlier on, we can ultimately efficiently treat a person’s symptoms and prevent the virus from developing into a more serious infection.”By determining if there is a correlation with a cell’s electrical signal and the presence – no matter how little the concentration – of NS1, we can identify if someone is infected with Dengue virus earlier.”last_img read more

Risk of stillbirth increases by continuing pregnancy to 41 weeks gestation

first_imgMore than 3,000 babies are stillborn every year in the UK – a third of these are term babies (37 weeks or beyond) who were considered to be ‘healthy’ prior to their death. Prolonged pregnancy is a known risk factor for stillbirth and women are routinely offered induction of labor after 41 weeks’ gestation. This recommendation is based on evidence of increased stillbirth risk beyond 41 weeks. However, one in three women with a stillbirth at term loses her baby before this period. The magnitude of this risk is not routinely communicated due to a previous lack of robust evidence.Related StoriesPersonalizing Nutritional Medicine With the Power of NMRIt is okay for women with lupus to get pregnant with proper care, says new studyMaternal obesity may negatively affect children’s lung developmentThe researchers have now analyzed data from 13 separate studies in the UK, US, Denmark and Norway, which included 15,124,027 pregnancies, 17,830 stillbirths and 2,348 newborn deaths.Despite the stillbirth risk figures, delivery before 41 weeks did not increase the risk of newborn death (defined as a death during the first 28 days of life) – the risk was unchanged for births between 38 and 41 weeks of gestation. The risk increased by 87 per cent for deliveries at 42 weeks’ gestation compared to 41 weeks.Professor Thangaratinam added: “This is the largest study of its kind, and finally provides precise estimates of potential risks of stillbirth. Now that we understand the extent to which stillbirth risks increase with each week of pregnancy, we should be incorporating this information in all discussions around delivery plans in pregnant women at term.”We were surprised to see how much poorer pregnancy outcomes were for Black women – they were up to twice more likely to experience stillbirth than White women. Healthcare professionals need to take these added risks into account when developing care plans for these women.”Limitations of the study include variations in the definitions of low risk pregnancy, the wide time-span of the studies, loss of data due to exclusion of studies that did not provide stillbirth estimates in weekly intervals, and potential confounders affecting the outcome. Source:Queen Mary University Of LondonJournal reference:Muglu, J. et al. (2019) Risks of stillbirth and neonatal death with advancing gestation at term: A systematic review and meta-analysis of cohort studies of 15 million pregnancies. PLOS Medicine. doi.org/10.1371/journal.pmed.1002838 . While there is an additional risk of stillbirth at 41 weeks, compared to 40 weeks, it is small. Women who prefer not to have medical interventions such as induction of labor may therefore acknowledge this small additional risk, and choose to wait until 41 weeks so that they have more time to go into labor naturally. Meanwhile, other women may prefer to have discussions with their healthcare providers on induction after 40 weeks. So this is all about helping women make informed decisions on timing of delivery.” Reviewed by James Ives, M.Psych. (Editor)Jul 3 2019With every week that a pregnancy continues past term (37 weeks), the risk of stillbirth increases, according to an analysis of more than 15 million pregnancies led by Queen Mary University of London.The results, published in the journal PLOS Medicine, also included a small but significantly increased risk of stillbirth in mothers who continued their pregnancy to 41 weeks’ gestation (when women are routinely offered induction of labor), compared to those who delivered at 40 weeks.The researchers say that women who are 41 weeks pregnant should not be alarmed, as the risk is low – equivalent to one additional stillbirth for every 1,449 pregnancies, compared to delivering at 40 weeks.Compared to White women, Black women at term were also found to be 1.5 to 2 times more likely to suffer stillbirth at all gestational ages.Lead Researcher Professor Shakila Thangaratinam from Queen Mary University of London:last_img read more

New US tax law brings Warren Buffett a nice check 29 billion

Berkshire Hathaway, the holding company of US billionaire investor Warren Buffett, received a stunning $29 billion check last year from the US government, thanks to a new tax law that massively lowered corporate tax rates. Investor Warren Buffett, seen here speaking at an event early last year in New York with fellow billionaire Bill Gates, says in his new newsletter that his company received a $29 billion bonus in 2017 thanks to a new US tax law This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Buffett’s company adds to stakes in Apple and Phillips 66 (Update) Explore further © 2018 AFP Citation: New US tax law brings Warren Buffett a nice check: $29 billion (2018, February 24) retrieved 18 July 2019 from https://phys.org/news/2018-02-tax-law-warren-buffett-nice.html In his much-anticipated annual letter to shareholders, Buffett explained that the company’s net gain of $65.3 billion in 2017 was only partly due to his employees’ efforts.”Only $36 billion came from Berkshire’s operations,” he wrote. “The remaining $29 billion was delivered to us in December when Congress rewrote the US Tax Code.” Still, Buffett assured stockholders, “The $65 billion gain is nonetheless real—rest assured of that.”The new law, greatly touted by President Donald Trump, lowered the tax rate paid by US corporations from 35 percent to 21 percent, allowing many to undertake major new outlays and others to book significant fiscal gains.Berkshire Hathaway wholly owns dozens of companies—from Dairy Queen to Duracell—and holds significant shares in large and diverse corporations including American Express, Apple, Bank of America, Charter Communications, Coca-Cola, Delta Air Lines, General Motors, Goldman Sachs, Moody’s, Wells Fargo and Southwest Airlines.’The Oracle of Omaha’Buffett’s newsletters are read with intense interest on Wall Street and beyond. Known as the “Oracle of Omaha”—after his birthplace in the Midwestern state of Nebraska—he is one of the world’s most successful investors and one of its richest men. Now 87, he has been investing since he first bought stock at the age of 11.His latest newsletter reports that Berkshire’s net earnings rose last year from $24.07 billion to $44.94 billion. The year also saw the company’s war chest swell to $116 billion in cash and US Treasury bills, financial manna that Buffett wants to use to make significant new acquisitions.The company’s often-impressive pace of acquisitions had slowed last year, he noted, when the prices asked for businesses “hit an all-time high,” amid what he called “a purchasing frenzy.” “Price seemed almost irrelevant to an army of optimistic purchasers,” Buffett noted.Still, he said, the company “will have opportunities to make very large purchases” going forward, with emphasis on those available at “a sensible purchase price.” Buffett said Berkshire would stick with a “simple guideline: The less the prudence with which others conduct their affairs, the greater the prudence with which we must conduct our own.”A hit from hurricanesBuffett also said that while Berkshire’s insurance holdings would take a $2 billion after-tax hit from losses caused by hurricanes last year in Florida, Texas and Puerto Rico, other reinsurance companies did far worse.And he estimated the chances of a “mega-catastrophe” this year—one causing losses of at least $400 billion—at 2 percent.”No one, of course, knows the correct probability,” he added. Buffett concluded with a little advice to fellow investors: “Though markets are generally rational, they occasionally do crazy things,” he wrote.”Seizing the opportunities then offered does not require great intelligence… (or) a degree in economics,” but rather “an ability to both disregard mob fears or enthusiasms and to focus on a few simple fundamentals.”Forbes magazine estimates Buffett’s personal worth at some $87 billion. He has undertaken—as part of the so-called Giving Pledge he co-founded with Bill Gates and Facebook CEO Mark Zuckerberg—to donate more than 99 percent of his fortune to charities, and has already given away some $32 billion. read more

What Is the Ionosphere And Who Is Steve

first_img Light up the skies The scorching-hot surface of the sun expels streams of highly charged particles, and these streams are known as solar wind. According to NASA’s Marshall Space Flight Center, solar wind flies through space at about 25 miles (40 km) per second. Upon reaching the Earth’s magnetic field and the ionosphere below, solar winds set off a colorful chemical reaction in the night sky called an aurora. When solar winds whip across Earth, the planet stays shielded behind its magnetic field, also known as the magnetosphere. Generated by churning molten iron in the Earth’s core, the magnetosphere sends solar radiation racing toward either pole. There, the charged particles collide with chemicals swirling in the ionosphere, generating the spellbinding auroras. Scientists have found that the sun’s own magnetic field squishes the Earth’s weaker one, shifting auroras toward the night side of the planet, as reported by Popular Mechanics. Near the Arctic and Antarctic circles, auroras streak across the sky every night, according to National Geographic. The colorful curtains of light, known as the aurora borealis and aurora australis, respectively, hang about 620 miles (1,000 km) above the Earth’s surface. The auroras glow green-yellow when ions strike oxygen particles in the lower ionosphere. Reddish light often blooms along the auroras’ edges, and purples and blues also appear in the nighttime sky, though this happens rarely. “The cause of aurora is somewhat known, but it is not entirely resolved,” said Toshi Nishimura, a geophysicist at Boston University. “For example, what causes a particular type of color of aurora, such as purple, is still a mystery.” Aurora Phenomena Named STEVE Explained by NASAVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Better Bug Sprays?01:33关闭选项Automated Captions – en-US facebook twitter 发邮件 reddit 链接https://www.livescience.com/65947-ionosphere.html?jwsource=cl已复制直播00:0002:1202:12Your Recommended Playlist01:33Better Bug Sprays?01:08Why Do French Fries Taste So Bad When They’re Cold?04:24Sperm Whale Befriends Underwater Robot00:29Robot Jumps Like a Grasshopper, Rolls Like a Ball00:29Video – Giggly Robot02:31Surgical Robotics关闭  This amateur astronomer’s photograph, taken on May 8, 2016, in Keller, Washington, was used in the new research about the celestial phenomenon called STEVE. The major structures are two bands of upper atmospheric emissions located 100 miles (160 kilometers) above the ground: a reddish arc and a green picket fence. Credit: Rocky Raybell Who is Steve? Beyond auroras, the ionosphere also plays host to other impressive light shows. In 2016, citizen scientists spotted a particularly eye-catching phenomena, which scientists struggled to explain, Live Science sister-site Space.com previously reported. Bright rivers of white and pinkish light flowed over Canada, which is farther south than most auroras appear. Occasionally, dashes of green joined the mix. The mysterious lights were named Steve in homage to the animated movie “Over the Hedge” and were later rebranded as the “Strong Thermal Emission Velocity Enhancement” ⁠— still STEVE for short. “We’ve been studying the aurora for hundreds of years, and we couldn’t, and still can’t, explain what Steve is,” said Gareth Perry, a space weather scientist at the New Jersey Institute of Technology. “It’s interesting because its emissions and properties are unlike anything else we observe, at least with optics, in the ionosphere.” According to a 2019 study in the journal Geophysical Research Letters, the green streaks within STEVE may develop similarly to how traditional auroras form, as charged particles rain down upon the atmosphere. In STEVE, however, the river of light seems to glow when particles within the ionosphere collide and generate heat among themselves. Check out a slideshow of fantastic auroras from National Geographic. Communication and navigation Though reactions in the ionosphere paint the sky with brilliant hues, they can also disrupt radio signals, interfere with navigational systems and sometimes cause widespread power blackouts. The ionosphere reflects radio transmissions below 10 megahertz, allowing the military, airlines and scientists to link radar and communication systems over long distances. These systems work best when the ionosphere is smooth, like a mirror, but they can be disrupted by irregularities in the plasma. GPS transmissions pass through the ionosphere and therefore bear the same vulnerabilities. “During large geomagnetic storms, or space weather events, currents [in the ionosphere] can induce other currents in the ground, electrical grids, pipelines, etc. and wreak havoc,” Perry said. One such solar storm caused the famous Quebec blackout of 1989. “Thirty years later, our electrical systems are still vulnerable to such events.” Scientists study the ionosphere using radars, cameras, satellite-bound instruments and computer models to better understand the region’s physical and chemical dynamics. Armed with this knowledge, they hope to better predict disruptions in the ionosphere and prevent problems that can cause on the ground below. Additional resources:by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 min and see why everyone is addicted!Vikings: Free Online GameUndoTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndoKelley Blue Book2019 Lexus Vehicles Worth Buying for Their Resale ValueKelley Blue BookUndoArticles VallyDad Cuts Daughter’s Hair Off For Getting Birthday Highlights, Then Mom Does The UnthinkableArticles VallyUndoBirch Gold GroupThis IRS Tax Law is Sweeping the U.S.Birch Gold GroupUndo A dense layer of molecules and electrically charged particles, called the ionosphere, hangs in the Earth’s upper atmosphere starting at about 35 miles (60 kilometers) above the planet’s surface and stretching out beyond 620 miles (1,000 km). Solar radiation coming from above buffets particles suspended in the atmospheric layer. Radio signals from below bounce off the ionosphere back to instruments on the ground. Where the ionosphere overlaps with magnetic fields, the sky erupts in brilliant light displays that are incredible to behold. Where is the ionosphere? Several distinct layers make up Earth’s atmosphere, including the mesosphere, which starts 31 miles (50 km) up, and the thermosphere, which starts at 53 miles (85 km) up. The ionosphere consists of three sections within the mesosphere and thermosphere, labeled the D, E and F layers, according to the UCAR Center for Science Education. Extreme ultraviolet radiation and X-rays from the sun bombard these upper regions of the atmosphere, striking the atoms and molecules held within those layers. The powerful radiation dislodges negatively charged electrons from the particles, altering those particles’ electrical charge. The resulting cloud of free electrons and charged particles, called ions, led to the name “ionosphere.” The ionized gas, or plasma, mixes with the denser, neutral atmosphere.Advertisement The concentration of ions in the ionosphere varies with the amount of solar radiation bearing down on the Earth. The ionosphere grows dense with charged particles during the day, but that density subsides at night as charged particles recombine with displaced electrons. Entire layers of the ionosphere appear and disappear during this daily cycle, according to NASA. Solar radiation also fluctuates over an 11-year period, meaning the sun may put out more or less radiation depending on the year. Explosive solar flares and gusts of solar wind stir up sudden changes in the ionosphere, teaming up with high-altitude winds and severe weather systems brewing on the Earth below. Learn how GPS works with the Smithsonian National Air and Space Museum. Earth’s ionosphere, a region of charged particles, stretches up to the border between Earth and space. Credit: NASA’s Goddard Space Flight Center, Duberstein Watch an animation of the Earth’s magnetic field in action, from Nova and the Khan Academy.last_img read more

Agricultural university to hold Krishi Mela in Dharwad from Sept 2225

first_imgSHARE SHARE EMAIL COMMENTS September 06, 2018 Published on Karnataka agricultural research and technology SHARE The University of Agricultural Sciences (UAS), Dharwad, plans to hold its annual four-day Krishi Mela from September 22-25. UAS has planned to organise Krishimela-2018 under the theme ‘Consume Millets-Conserve Health’ in collaboration with the Karnataka State Department of Agriculture and the National Bank for Agriculture and Rural Development (Nabard) at the main campus in Dharwad.“This year UAS is expecting more than 10 lakh farmers, farm women, extension workers and rural youth to take part from Karnataka and neighbouring states,” said R R Patil, Director of Extension, UAS-Dharwad.The mega event will provide a platform to showcase and educate stakeholders on the agriculture and allied technologies released by the university and private enterprises. In addition, a millets corner, sale of seeds, fertilisers, chemicals, biofertilisers and biopesticides will be undertaken.During the mela, UAS is to hold a demonstration of farm mechanisation activities by the manufacturers of agriculture implements. “During Krishi Mela, the university would organise bus arrangements within the campus for farmers to visit various crop demonstrations,” said Patil. COMMENTlast_img read more

TN has taken steps for water resources management CM

first_imgCOMMENTS SHARE SHARE EMAIL SHARE COMMENT Tamil Nadu March 30, 2019center_img Published on elections The Tamil Nadu Chief Minister Edappadi K Palaniswami during the election campaign along with S. Asaimani, Mayiladuthurai Lok Sabha candidate, on Saturday. – Photo: M Moorthy The AIADMK government in Tamil Nadu has taken extensive steps for water resources conservation and management across the State, Chief Minister K Palaniswami said on Saturday.Addressing an election meeting, he said the government has accorded top priority for the welfare of farmers and desiltation works had been taken up at a cost of Rs 3,000 crore in delta districts. Palaniswami said a special team headed by four experts has been set up to identify places where check dams have to be constructed with a view to preventing rain water from flowing into the sea during the monsoon season.“Our government has taken extensive steps for conservation and management of water resources. We are determined to implement a new combined water scheme for this area,” he said while campaigning for the party’s candidate from Mayiladuthurai Lok Sabha constituency S Asaimani. Travelling between Sirkazhi and Mayiladuthurai, the Chief Minister stopped his campaign vehicle near paddy fields at a few places and interacted with farmers.last_img read more

Election Commission gives Modi the clean chit on poll code violation chargeElection

first_imgPrime Minister Narendra Modi   –  – COMMENTS SHARE Elections 2019 Published on Election Commission of Indiacenter_img SHARE SHARE EMAIL April 30, 2019 Prime Minister Narendra Modi has been given a clean chit by the Election Commission for delivering a speech in Wardha on April 1. Sources said, after going through the report of the Chief Electoral Officer Maharashtra, the EC examined the matter in detail and found no such violation of the Model Code of Conduct (MCC).”The Opposition had complained that the Prime Minister in his speech had violated the MCC as he said Rahul Gandhi had decided to all contest from Wayanad because the ‘majority’ was in ‘minority’ there and that he was scared. There were allegations that Modi had violated the MCC as he was campaigning for votes using religion.The Commission order giving a clean chit to Modi comes before Varanasi — the constituency from which the Prime Minister is contesting — going to polls on May 19, the last and final stage of the seven-phase election. The fifth stage of the election is scheduled for May 6 while the sixth will be on May 12. Till the completion of the fourth phase of elections on April 29, 68 per cent of the seats to the Lok Sabha had already been voted for.The Commission was also to examine the MCC violations that BJPPresident Amit Shah and Congress President Rahul Gandhi have allegedly committed during their various election speeches. But the Commission’s order on Shah and Gandhi was not available.Campaign ban on Azam KhanThe Commission also decided to bar Azam Khan for campaigning for 48 hours from 6 am on May 1. COMMENTlast_img read more

Many districts in Uttar Pradesh stare at floods as rains swell rivers

first_img Nelanshu Shukla LucknowJuly 14, 2019UPDATED: July 14, 2019 22:19 IST The water level in the river Ganga in Varanasi has risen due to rainfall.HIGHLIGHTSIncessant rains since last few days have increased the water level in Sangam riverA flood like situation is being witnessed in low lying areas close to Sangam riverWater has also entered in temples situated on the banks of river GangaHeavy rainfall in some of the districts in Uttar Pradesh particularly in the eastern part have increased water level in major rivers.Incessant rains since last few days have increased the water level in Sangam river affecting the lives of the people living in the nearby areas. A flood like situation is being witnessed in low lying areas close to the river. Due to that, many people have been moved to safer places.The water level in the river Ganga in Varanasi has also risen due to rainfall and people living close to the banks have migrated to other areas. The local administration is also helping the people who are forced to shift due to the flood-like situation. Water has also entered in temples situated on the banks of river Ganga while heavy water logging has been reported in the area.The district administrations in Bahraich, Gonda, Lakhimpur Kheri, Gorakhpur, Barabanki have sounded a high alert have sounded a high alert in the wake of floods in Nepal which has claimed lives of over 40 people.Arrangements are already in place to shift people to safer places in areas close to Nepal.Meanwhile, the state capital Lucknow witnessed cloudy sky on Sunday with maximum temperature of 36.3 degrees celsius.According to the meteorological department, Aligarh was the hottest city in the state, where mercury touched 38.6 degrees celsius, followed by Kanpur which recorded a high of 37.6 degrees Celsius. Banda and Agra — each recorded a maximum of 37.2 degrees Celsius.The meteorological department also said that heavy rain is very likely at isolated places over the state on July 15.ALSO READ | Heavy rains trigger flash floods in Nepal, leave 34 deadALSO WATCH | In Depth: Decoding the link between floods and droughtsFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted bySnigdha Choudhury Next Many districts in Uttar Pradesh stare at floods as rains swell riversIncessant rains since last few days have increased the water level in Sangam river affecting the lives of the people living in the nearby areas.advertisementlast_img read more